allopurinol side affects - Uric Acid Testing
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Uric Acid Testing

Definition

Uric acid tests are tests that are done to measure the levels of uric acid in blood serum or in urine.

Purpose



Urine test

Patients should be checked for the following medications before the urine test: diuretics, aspirin, pyrazinamide (Tebrazid), phenylbutazone, probenecid (Benemid), and allopurinol (Lopurin). If the patient needs to continue taking these medications, the laboratory should be notified. Using the intuition I had on Uric Acid Gout, I thought that writing this article would indeed be worth the trouble. Most of the relevant information on Uric Acid Gout has been included here.


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Certain foods that are high in purine may increase the patient's levels of uric acid. These include kidneys, liver, sweetbreads, sardines, anchovies, and meat extracts. Writing something about Uric Acid Gout seemed to be something illogical in the beginning. However, with the progress of matter, it seemed logical. Matter just started pouring in, to give you this finished product.

Normal results

Blood test

Reference values for blood uric acid vary from laboratory to laboratory but are generally found within the following range: Male: 2.1-8.5 mg/dL; female: 2.0-6.6 mg/dL. Values may be slightly higher in the elderly. We had at first written a rough assignment on Uric Acid Test. Then after a few improvisions and enhancements here and there, we have ended up with this end product.

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Risks

Risks for the blood test are minimal, but may include slight bleeding from the puncture site, a small bruise or swelling in the area, or fainting or feeling lightheaded. We were a bit tentative when embarking on this project on Allopurinol. However, using the grit and determination we have, we have produced some fine reading material on Allopurinol.

Description

The uric acid blood test is performed on a sample of the patient's blood, withdrawn from a vein into a vacuum tube. The procedure, which is called a venipuncture, takes about five minutes. The urine test requires the patient to collect all urine voided over a 24-hour period, with the exception of the very first specimen. The patient keeps the specimen container on ice or in the refrigerator during the collection period. Coordinating matter regarding to Uric Acid Blood Test took a lot of time. However, with the progress of time, we not only gathered more matter, we also learnt more about Uric Acid Blood Test.

Increased production of uric acid may result from eating foods that are high in purine. Increased uric acid levels due to overproduction may also be caused by gout, by a genetic disorder of purine metabolism, or by metastatic cancer, destruction of red blood cells, leukemia, or cancer chemotherapy. This article will help you since it is a comprehensive study on Uric Acid Test

The Internet Guide: Gout - http://gout.smartadsscrets.com The Internet Guide: Purines - http://gout.smartadssecrets.com/purines Isn't it wonderful that we can now access information about anything, including Uric Acid Kidneys form the Internet without the hassle of going through books and magazines for matter!

Decreased excretion of uric acid is seen in chronic kidney disease, low thyroid, toxemia of pregnancy, and alcoholism. Patients with gout excrete less than half the uric acid in their blood as other persons. Only 10-15% of the total cases of hyperuricemia, however, are caused by gout. The more you read about Uric Acid Gout, the more you get to understand the meaning of it. So if you read this article and other related articles, you are sure to get the required amount of matter for yourself

If you wish to learn more about Gout, Purines, or Uric Acid, check out Steve's s The Internet Guides. The Internet Guide: Uric Acid: http://gout.smartadssecrets.com/uric_acid When doing an assignment on Increased Uric Acid Levels, it is always better to look up and use matter like the one given here. Your assignment turns out to be more interesting and colorful this way.

Abnormal results

The critical value for the blood test is a level of uric acid higher than 12 milligrams per deciliter (about 4 ounces). Learning about things is what we are living here for now. So try to get to know as much about everything, including Gout Purines whenever possible.

 
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Uric acid is a waste product that results from the breakdown of purine, a nucleic acid. (Nucleic acids are the building blocks of DNA.) Uric acid is made in the liver and excreted by the kidneys. If the liver produces too much uric acid or the kidneys excrete too little, the patient will have too much uric acid in the blood. This condition is called hyperuricemia. Supersaturated uric acid in the urine (uricosuria) can crystallize to form kidney stones that may block the tubes that lead from the kidneys to the bladder (the ureters).

Preparation

The uric acid test requires either a blood or urine sample. For the blood sample, the patient should be fasting (nothing to eat or drink) for at least eight hours before the test. The urine test for uric acid requires a 24-hour urine collection. The urine test does not require the patient to fast or cut down on fluids. Some laboratories encourage patients to drink plenty of fluids during the collection period.

The uric acid tests are used to evaluate the blood levels of uric acid for gout and to assess uric acid levels in the urine for kidney stone formation. The urine test is used most often to monitor patients already diagnosed with kidney stones, but it can also be used to detect disorders that affect the body's production of uric acid and to help measure the level of kidney functioning.

The laboratory should also be notified if the patient has had recent x-ray tests requiring contrast dyes. These chemicals increase uric acid levels in urine and decrease them in blood.

Abnormally low uric acid levels may indicate that the patient is taking allopurinol or probenecid for treatment of gout; may be pregnant; or suffers from Wilson's disease or Fanconi's syndrome.

Urine test

Reference values for 24-hour urinary uric acid vary from laboratory to laboratory but are generally found within the following range: 250-750 mg/24 hours. People always think that they know everything about everything; however, it should be known that no one is perfect in everything. There is never a limit to learning; even learning about Uric Acid.

Key Terms

Fanconi's syndrome
A rare disorder caused by vitamin D deficiency or exposure to heavy metals.
Gout
A metabolic disorder characterized by sudden recurring attacks of arthritis caused by deposits of crystals that build up in the joints due to abnormally high uric acid blood levels. In gout, uric acid may be overproduced, underexcreted, or both.
Hyperuricemia
Excessively high levels of uric acid in the blood, often producing gout.
Purine
A white crystalline substance that is one of the building blocks of DNA. Uric acid is produced when purine is broken down in the body.
Uric acid
A compound resulting from the body's breakdown of purine. It is normally present in human urine only in small amounts.
Uricosuria
Increased levels of uric acid in the urine.
Wilson's disease
A rare hereditary disease marked by the buildup of copper in the liver and brain, causing loss of kidney function.

Further Reading

For Your Information

    Books

  • Laboratory Test Handbook, edited by David S. Jacobs. Cleveland, OH: Lexi-Comp Inc., 1996.
  • Mosby's Diagnostic and Laboratory Test Reference, edited by Kathleen Deska Pagana and Timothy James Pagana. St. Louis: Mosby-Year Book, Inc., 1998.
  • Springhouse Corporation. Handbook of Diagnostic Tests, edited by Matthew Cahill. Springhouse, PA: Springhouse Corporation, 1995.

Bio

There has been a gradual introduction to the world of Uric Acid Levels projected in this article. We had done this so that the actual meaning of the article will sink within you.




 
 
     
 
 





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